Pathological correlates of dementia in Alzheimer's disease.
D Mann - 1994 - psycnet.apa.org
D Mann
1994•psycnet.apa.orgComments on the conclusion by L. Regeur et al (see record 1995-22109-001) that there is
no global neuronal loss in Alzheimer's disease (AD). Although it is possible that the data
presented by Regeur may accurately represent the situation within their small cohort of
elderly AD patients, the generality of such findings as applied to AD as a whole is less
certain. Finding a single pathologic predictor of the extent of clinical disease is problematic.
Given the complexity of the pathologic process of AD, it is hardly to be expected that a single …
no global neuronal loss in Alzheimer's disease (AD). Although it is possible that the data
presented by Regeur may accurately represent the situation within their small cohort of
elderly AD patients, the generality of such findings as applied to AD as a whole is less
certain. Finding a single pathologic predictor of the extent of clinical disease is problematic.
Given the complexity of the pathologic process of AD, it is hardly to be expected that a single …
Abstract
Comments on the conclusion by L. Regeur et al (see record 1995-22109-001) that there is no global neuronal loss in Alzheimer's disease (AD). Although it is possible that the data presented by Regeur may accurately represent the situation within their small cohort of elderly AD patients, the generality of such findings as applied to AD as a whole is less certain. Finding a single pathologic predictor of the extent of clinical disease is problematic. Given the complexity of the pathologic process of AD, it is hardly to be expected that a single (morphological) change can wholly predict the extent of clinical disturbance.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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