Continuous-flow left ventricular assist device–related gastrointestinal bleeding

JH Kim, DF Brophy, KB Shah - Cardiology Clinics, 2018 - cardiology.theclinics.com
Continuous-flow (CF) left ventricular assist device (LVAD) therapy for patients with advanced
heart failure continues to increase both as a bridge to transplant (BTT) and as destination
therapy (DT) for those with contraindications to heart transplant. Recent analysis of the
Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) showed
that, of the more than 20,000 implants of LVADs that have been reported to the registry since
2006, most are CF devices. 1 CF LVADs increase bleeding risk by activating the coagulation …