Importance Genetic studies have evaluated the influence of blood lipid levels on the risk of
coronary artery disease (CAD), but less is known about how they are associated with the
extent of coronary atherosclerosis. Objective To estimate the contributions of genetically
predicted blood lipid levels on the extent of coronary atherosclerosis. Design, Setting, and
Participants This genetic study included Icelandic adults who had undergone coronary
angiography or assessment of coronary artery calcium using cardiac computed tomography …