Biochemical aspects of malabsorption in marasmus

HC Mehta, AS Saini, H Singh, PS Dhatt - British journal of nutrition, 1984 - cambridge.org
HC Mehta, AS Saini, H Singh, PS Dhatt
British journal of nutrition, 1984cambridge.org
1. Sixty marasmic children and fifteen normal age-matched controls were investigated for the
absorption of fats and proteins. Their duodenal juice samples were also analysed for bile
salts and microflora. 2. A significant amount of malabsorption, with respect to both the dietary
ingredients, was observed in the majority of the marasmic children. 3. The levels of
conjugated bile acids in the duodenal juice samples of marasmic children were significantly
lower as compared with those of normal controls, while the reverse was true for free bile …
1. Sixty marasmic children and fifteen normal age-matched controls were investigated for the absorption of fats and proteins. Their duodenal juice samples were also analysed for bile salts and microflora.2. A significant amount of malabsorption, with respect to both the dietary ingredients, was observed in the majority of the marasmic children.3. The levels of conjugated bile acids in the duodenal juice samples of marasmic children were significantly lower as compared with those of normal controls, while the reverse was true for free bile acids and bacterial counts.4. Significant correlations were observed between bile acid levels and fat absorption and also between microflora and free bile acids.5. The pathophysiology of malabsorption in marasmus is discussed in the light of these findings.
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