Esophageal cancer remains an important public health problem worldwide. Understanding
and preventing the occurrence of this cancer are complicated by the fact that the 2 major
histologic types, squamous cell carcinoma (SCC) and adenocarcinoma (ACE), differ
substantially in their underlying patterns of incidence and key etiologic factors. The main
characteristic that they share is a high mortality rate. Surveillance, Epidemiology, and End
Results data for the United States show a 30% drop in incidence of SCC between 1973 and …