Effect of ERK inhibitor on pulmonary metastasis of inoculated human adenoid cystic carcinoma cells in nude mice

J Hu, Y Li, J Fang - Oral Surgery, Oral Medicine, Oral Pathology, Oral …, 2010 - Elsevier
In this study, we detected the expression of phosphylated ERK1/2 in human salivary
adenoid cystic carcinoma (SACC) by immunohistochemical method, the effect of various
concentrations of PD98059 on the growth of ACC-M cells (a cell line of human adenoid
cystic carcinoma of the salivary glands) by MTT assay, and the effect of PD98059 on the
lung metastasis of inoculated ACC-M cells in nude mice. The results showed that the
phosphylated ERK1/2 was overexpressed in SACC, the ACC-M cell line proliferation was …